Hypertonic nonketogenic diabetic coma

Diabetic hypertonic coma (HNDC) is a rare serious acute complication of diabetes. It is more common in elderly patients with no history of diabetes or mild non-insulin-dependent diabetes mellitus, but also in patients with insulin-dependent diabetes mellitus. The patient's original insulin secretion was insufficient, and the blood glucose rose sharply under the inducement, which promoted the increase of glucose metabolism disorder, causing extracellular fluid to become hypertonic, and hypovolemic hypertonic dehydration occurred. The original arteriosclerosis caused insufficient and insufficient blood supply to the cerebral cortex. Oxygen, causing neurological symptoms and coma.