Autoimmune hemolytic anemia

Autoimmune hemolytic anemia (AIHA) is a group of anemia caused by abnormally high B-lymphocyte function, production of anti-red blood cell antibodies, and increased destruction of red blood cells. Sometimes the destruction of red blood cells can be compensated by the generation of red blood cells in the bone marrow. Anemia does not occur clinically, that is, only autoimmune hemolysis (AIH). Others can only detect anti-erythrocyte antibodies (AI) without obvious signs of hemolysis. When the body produces both anti-self-erythrocyte antibodies and anti-self-platelet antibodies (even leukocyte antibodies), and then anemia and thrombocytopenia (or whole cell reduction) occur simultaneously, it is called Evans. The clinical manifestations of this disease are various. Warm antibody type AIHA is chronic onset and easy to repeat. Some patients have a history of acute attacks. During the attack, chills, fever, jaundice, back pain, etc. are seen. Hemoglobinuria is common in paroxysmal cold Hemoglobinuria is rare in cold agglutinin disease, the condition is often repetitive, and it is not easy to control at later stages.