Serum uric acid

Uric acid is the final product of purine catabolism. Excreted by the kidneys with urine. The content of uric acid in healthy adults is about 1.1g, about 15% of which is in the blood. After filtering through the glomerulus, most of the uric acid in the blood is reabsorbed by the tubules. Uric acid is one of the important components of non-protein nitrogen in the plasma. In severe kidney damage, the blood uric acid can be significantly increased. It does not change much when it is slightly damaged. Therefore, the determination of blood uric acid is a sensitive indicator for diagnosis of severe renal impairment.