Subacute infective endocarditis

Subacute infective endocarditis often occurs on the basis of heart disease such as rheumatic heart valve disease, ventricular septal defect, open ductus arteriosus, etc. It can also occur in patients without original heart disease. Pathogens are mainly bacteria, followed by fungi, rickettsiae, chlamydia and viruses. Mainly manifested as low to moderate fever, progressive anemia, fatigue, night sweats, hepatosplenomegaly, clubbing fingers (toes), vascular embolism may occur, and there are more young and middle-aged patients. In recent years, it has been found that the disease has an increasing trend on the basis of mitral valve prolapse, cardiac catheterization and cardiac surgery, and senile valve degeneration, and the age of onset has gradually increased. Streptococcus grass green is the most important pathogen of the disease, but it has been significantly reduced in recent years. Various staphylococci, hemolytic streptococci, enterococci and gram-negative bacteria have become the main pathogens.