Urinary bilirubin

Bilirubin is produced metabolically after the destruction of red blood cells. It can be divided into unconjugated bilirubin without liver treatment and bound bilirubin formed by combining liver with glucuronic acid. Unbound bilirubin is insoluble in water and cannot bind to proteins in the blood through the glomerular filter. Combined with a small molecular weight and high solubility, bilirubin can be excreted from the urine through the glomerular filter. Due to the low content of bound bilirubin in normal people and very little excess filtration, no bilirubin can be detected in urine. If the amount of bilirubin in blood increases, the amount of bilirubin bound in urine can be passed through the glomerular membrane Increase in urine bilirubin test volume was positive.