Lying test

The supine test is performed by the following principles. Normal people stay in bed overnight, and the plasma aldosterone value is about 110-330 pmol / L at 8 am. When they remain in the supine position until 12 noon, the plasma aldosterone concentration decreases and the plasma cortisol concentration The decrease is consistent; if standing, the plasma aldosterone rises because the effect of elevated renin-angiotensin after standing exceeds that of ACTH. Patients with special aldehyde disease have risen in plasma aldosterone from 8 to 12 in the morning and exceed normal people. Because the patient has a slight rise in plasma renin after standing, plus this type has increased sensitivity to angiotensin; aldosterone Under this condition, plasma aldosterone does not rise, but falls, because the patient's renin-angiotensin system is more severely inhibited and cannot rise after standing. Renin-responsive adenomas. Plasma renin changes caused by standing position significantly increase blood aldosterone.