Urine Ketone Test

The three substances acetoacetic acid, & beta; -hydroxybutyric acid and acetone are collectively called ketone bodies. Ketone body is a unique intermediate product of fatty acids during the decomposition and oxidation of the liver. It is a form of energy output by the liver. Because of its small molecular weight, it can dissolve in water and can pass through the blood-brain barrier and capillary walls. It is a muscle, especially brain tissue. Important energy. Long-term starvation, when the sugar supply is insufficient, ketone bodies can replace glucose and become the main energy source for brain tissue and muscle. The acetone concentration in normal human blood is about 0.03 to 0.5 mmol / L, and the amount of ketone body (calculated as acetone) in urine for 24 hours is about 0.34 to 0.85 mmol / L. The general test method is negative. During strenuous exercise, high-fat, low-sugar diet, hunger, hyperemesis gravidarum, stress, and diabetes, fat mobilization accelerates, and ketone body production increases, especially in diabetic patients who do not control their diet. Ketone body production is normally dozens of times. Times, of which acetone accounts for about half of the total amount of ketone bodies, far exceeding the ability of extrahepatic tissues to utilize ketone bodies, causing an increase in blood ketone body concentrations, and even causing ketoacidosis, which is formed with urinary excretion.