Human leukocyte antigen B27

Human leukocyte antigen B27 (HLA-B27) is a labeled antibody to rheumatoid arthritis (RA), with high specificity, and has diagnostic significance for early rheumatoid arthritis or rheumatoid arthritis with atypical clinical symptoms. HLA-B27 is closely related to ankylosing spondylitis (AS). HLA-B27 is positive in 90% of AS patients, while the positive rate in normal people is only 4% to 7%. But not HIA-B27-positive people will develop AS. According to statistics, about 20% of HLA-B27-positive people develop AS or other serum-negative spinal arthropathy, such as Reiter's syndrome, reactive arthropathy, and psoriasis Disease, etc.