Estriol

Estriol (E3) is a metabolite of estradiol and estrone, and its value is very low during non-pregnancy, and is mainly synthesized by the liver; it is mainly synthesized by the fetal placenta during pregnancy, and is metabolized in the liver through maternal blood circulation after synthesis, and Sulfuric acid or glucuronic acid combine to form bound E3, which is excreted from the urine. E3 plays an important role in the regulation of fetal intrauterine development and can affect the sensitivity of the pregnant uterus to oxytocin.