Urinary manganese

The human body contains 12 to 18 mg of manganese. Manganese is mainly absorbed in the intestine, and is excreted into the feces with bile through the liver. Urinary manganese excretion is less than 10% of total excretion. The accumulation of manganese in bone accounts for about 43% of the total body. Because manganese participates in the composition and activation of various enzymes, it is not only related to protein synthesis, but also can improve lipid metabolism in atherosclerosis. Manganese can also promote iron absorption and utilization, participate in mucopolysaccharide synthesis (mucopolysaccharide is the main component of cartilage and bone tissue), and can prevent oxidation and eliminate free radicals, playing a role in preventing cancer.