Gastric free hydrochloric acid

The free acid is hydrochloric acid, and the binding acid refers to hydrochloric acid that is loosely bound to proteins. Determination of gastric free hydrochloric acid can understand the secretion of gastric acid, which has an auxiliary role in the diagnosis of gastric related diseases. Increased gastric acid is found in ulcer disease, hyperacid gastritis, pyloric obstruction, and gastrinoma (the secretion of gastric acid is often 3-6 times more than normal people). Gastric acid reduction is seen in atrophic gastritis, gastric dilatation, secondary iron deficiency anemia, malignant anemia, and gastric cancer. In the case of true gastric acid deficiency, gastric acid does not increase after a test meal or histamine injection, but it is also occasionally seen in the elderly without ascorbic acid.