Islet cell destruction

Diabetes mellitus is a metabolic disorder caused by insulin deficiency or (and) reduced biological effects of insulin. It is a common disease that is characterized by persistently elevated blood glucose and the appearance of diabetes, with an incidence of 1% to 2%. The so-called daily diabetes refers to primary diabetes, which can be divided into pancreatin-dependent diabetes mellitus (type 1 diabetes) and non-insulin-dependent diabetes mellitus (type 2 diabetes) according to its etiology, pathogenesis, disease, clinical manifestations and prognosis ). Insulin-dependent diabetes can occur at any age, but it usually occurs in children or adolescents. It accounts for less than one percent of all diabetes, but its impact on life is far greater than the common non-insulin-dependent diabetes. The exact cause of insulin-dependent diabetes is not very clear. It is relatively certain that the body's immune system has a problem and fights against its own body tissues. The body's immune system creates certain substances that fight beta cells that secrete insulin from the pancreas. When these cells are destroyed, they cannot secrete insulin.