Primary hepatic liposarcoma

Liposarcoma is a malignant tumor that originates from primitive mesenchymal tissue. It often occurs in the thighs and peritoneum, and can also be found in the hips and rostral fossa. Soft tissues in other parts are also rare, and rarely occur in the liver. The pathological morphology of primary liposarcoma of the liver is very similar to that of liposarcoma of other parts. The tumor is oval or irregular, soft, and often not found until the volume is large. The cut surface of the tumor is grayish yellow. Or grayish white, common necrotic area, the necrotic area is easy to soften and fragile, the tissue around the tumor is compressed, and an incomplete thin layer of pseudo-envelope can be formed. A well-differentiated liposarcoma can have a complete envelope. There are mature mature adipocytes and immature mesenchymal cells and heteromorphic cells in different stages of liposarcoma. Lipid vacuoles are visible in the cytoplasm, and the nucleus is oval or round, with coarse particles, deep staining, and visible mucinous patterns. There is a rich mucus-like matrix between the cells. Asin blue staining is positive, and the surrounding liver tissue has no cirrhosis. Liposarcoma is a moderately malignant tumor in soft tissue sarcomas. The 5-year survival rate can reach 35% to 40%, and about 40% to 50% of liposarcomas have lung metastases. The main age of onset is middle to late age. In terms of liver primary liposarcoma, two were middle-aged women and two were children. Two domestic cases were reported as adults, one male and one female, with well-differentiated and myxoid-like types. It is reported that there is a lack of information on its prognosis.