Serum soluble transferrin receptor

The soluble transferrin receptor assay is a routine receptor check for soluble transferrin in humans. The soluble transferrin receptor (sTfR) is derived from the proteolysis of cell surface receptors. STfR and different transferrins exist in the form of complexes in serum. Approximately 80% of sTfR in serum originates from early red blood cells. When the red blood cell production activity increases, especially when iron is deficient, it will cause an increase in sTfR synthesis. Increased sTfR concentration.