Medium dose dexamethasone inhibition test

The medium-dose dexamethasone inhibition test is carried out by the following principles: masculine congenital adrenal hyperplasia, such as patients with 21 hydroxylase deficiency due to cortisol synthesis disorders, ACTH feedback secretion increases, leading to adrenal hyperplasia and adrenal Increased ketones (increased urine 17-KS, 17-KGS). Given an appropriate amount of exogenous synthetic corticosteroid-dexamethasone to inhibit the excessive release of ACTH, the levels of urine 17-KS and 17-KGS decreased accordingly.