Helicobacter pylori infection

Helicobacter pylori is a spiral-shaped, Gram-negative, microaerobic bacterium. Almost half of the population is infected for life, and the infection is mainly in the stomach and duodenal bulb. As early as 1893, Bizzozero reported the observation of a spiral-shaped microorganism in the dog's stomach. Later, Kreintz and Rosenow also found Borrelia in the human stomach. In 1979, Warren found that most gastric mucosal biopsy specimens of patients with chronic gastritis and peptic ulcers settled with Campylobacter-like bacteria, which are regularly present on the surface of the mucosal cell layer and under the mucus layer. It is easy to use Warthin-Starry saturated silver Staining. It was not until 1983 that Marshall and Warren reported the first successful isolation of this bacteria using a microaerobic culture method of Campylobacter. Since then, it has aroused widespread interest and in-depth research in the medical profession. It was later found that many of the characteristics of this bacterium were similar to Campylobacter, and it was named "Campylobacter pylori (CP)".