Postpartum pituitary necrosis

Anterior pituitary hypofunction (also known as "Sheehan's disease") is caused by a variety of lesions of the pituitary or hypothalamus involving the endocrine function of the pituitary. When all or most of the pituitary gland is destroyed, a series of endocrine gland dysfunction can be produced. The main glands involved are the gonads, thyroid gland and adrenal cortex. This disease is more common in women and is mostly related to pituitary ischemic necrosis caused by postpartum hemorrhage.