Enterovirus 71 infection

Enterovirus 71 was first isolated from a second outbreak of central nervous system infection in California in the United States from 1969 to 1970, and spread to all parts of the world after 1970; in 1972, it caused a predominantly meningitis epidemic in Australia; 1973 In Japan, the prevalence of hand, foot, oral disease and / or aseptic meningitis was mainly caused in Japan. In Sweden, the predominance of aseptic meningitis was mainly caused by a small number of hand, foot and oral diseases. EV 71 was first isolated from a stool specimen of infants with central nervous system disease in California in 1969 and was identified and named in 1974. Since then, many countries have reported the epidemic of EV71. EV 71 infection was first discovered in mainland China in the winter of 1987, a hand-foot-and-mouth disease appeared in Hubei Province. In 1995, Wuhan Virus Research Institute isolated EV71 from patients with hand-foot-and-mouth disease. Caused by EV 71 infection.