Insulin resistance and metabolic syndrome

Insulin resistance is one of the hot issues that everyone pays attention to. As early as the 1960s, it was observed that impaired glucose tolerance (IGT), diabetes, obesity, lipid metabolism disorders and high blood pressure often appeared in the same individual at the same time. Some people called it the prosperity syndrome at that time, but for a long time People do not understand why the various components of the syndrome appear in the same individual or the same family one after the other, so they are also known as syndrome X. It was not until 1988 that Reaven first proposed the insulin resistance syndrome that people linked these multiple manifestations with insulin resistance, arguing that the common pathological basis for their pathogenesis was insulin resistance. Definition of insulin resistance: the body's reduced responsiveness or sensitivity to the physiological effects of insulin. Narrow insulin resistance refers to a decrease in the responsiveness of tissue cells to insulin-mediated glucose utilization. The main sites of insulin resistance are the liver, muscle and adipose tissue.