Vasotrophic leukoplakia

10% to 30% of patients with systemic lupus erythematosus can see reticular leukoplakia, which is a manifestation of small blood vessel inflammation and circulatory disorders. It is a narrowing of the arterial lumen of the skin of the extremities, dilation of the small veins, and a reticular pattern and branches on the skin surface. Red erythema and purpura, which often appear in cold conditions, may be related to cryoglobulinemia and anticardiolipin antibodies. Occurs around the thighs, calves, hands, back of feet, elbows, and knees. If there is necrotizing vasculitis, it is often accompanied by purple spots, gangrene, and ulcers. If the vascular disease is serious, skin lesions of plaque-like vasculitis may appear, which are manifested as leukoplakia with painful ulcers. After the ulcers heal, atrophic scars with hypopigmentation and telangiectasia, that is, atrophic leukoplakia.