Cryptococcus membrane polysaccharide accumulation

Cryptococcus mainly causes diseases of the central nervous system, lungs, and skin, and severe cases can be life-threatening. Disseminated lesions can also occur at the end of long bones, joints, liver, spleen, kidney, heart, testis, prostate and other organs. The typical affected tissue contains a capsule-like yeast sac, which is a accumulation of polysaccharides from the cryptococcus capsular membrane, but with only slight or no acute inflammation changes. In severe cases, sepsis can spread to various organs of the body and even cause death.