Vitamin B6 deficiency in children

Vitamin B6 deficiency is caused by improperly cooked food or too monotonous varieties. Malabsorption can also cause vitamin B6 deficiency. Vitamin B6 dependence syndrome is a structural and functional deficiency of the innate metabolic enzyme kynureninase. At this time, the requirement of vitamin B6 is 5 to 10 times that required by normal children, and vitamin B6 deficiency is extremely prone to occur. The main manifestation of vitamin B6 deficiency and dependence in infancy is generalized convulsions, leading to mental retardation. It is often accompanied by gastrointestinal symptoms such as vomiting and diarrhea. Other manifestations include peripheral neuritis, dermatitis, and anemia.