Organochlorine pesticide poisoning

Organochlorine insecticides can enter the body from the respiratory tract, digestive tract, and skin, and are mainly excreted by the kidneys. A small amount can also be excreted in feces and milk. Because it is a fat-soluble substance, it has a special affinity for fat-rich tissues and can accumulate in adipose tissues. The poisoning mechanism of this class of pesticides is generally considered to be the chain reaction of dechlorination when organic chlorine molecules (chlorinated hydrocarbons) enter the blood circulation and interact with oxygen-active atoms in the matrix, resulting in unstable oxygenated compounds, which slowly degrade A new activation center is formed, which strongly affects the surrounding tissues and causes serious pathological changes.