Pachyderm

Pachyermoperiostosis is also known as skin hypertrophic periosteal osteoplasty and Touraine-Solente-Gole syndrome. The primary may be autosomal dominant inheritance, and the secondary is also called hyperproliferative osteoarthropathy. Often secondary to various chronic and malignant tumor diseases, the pathogenesis is still unclear. Primary periosteal hyperplasia is mainly found in men, which may be an autosomal dominant genetic disease with different penetrances. Such cases have been reported in China. Secondary periosteal hyperplasia may also be a genetic disorder, but it is often triggered by severe liver disease, bronchogenic or epithelioid adenocarcinoma, bronchiectasis, lung abscess, or gastric, esophageal, and thymic cancers.