Pediatric tuberous sclerosis

Tuberous sclerosis, also known as Bourneville disease, is a multisystem involved neurocutaneous syndrome. The neurological symptoms and pathological changes were first described by Bourneville in 1880. In 1908, Heinrich Vogt pointed out the triad of the disease, namely epilepsy, mental retardation and facial hemangiofibroma. Can rely on clinical manifestations for diagnosis.