Pediatric Myelodysplastic Syndrome

Myelodysplastic syndromes (MDS), formerly known as pre-leukemia, is a group of damage that originates from hematopoietic stem / progenitor cell levels, lacks typical clinical manifestations, often has anemia, sometimes infection or bleeding, and some cases have hepatosplenomegaly. Big. Hematology showed a decrease in whole blood cells or any one or two lines of cells. Myeloid hyperplasia is active, and tertiary or secondary blood cells have significant morbid hematopoiesis with a slightly longer course. If they do not die from infection or bleeding, they often develop into leukemia or bone marrow hematopoietic failure. The annual incidence of MDS in children is about 4.0 / 100,000, accounting for 9% of children's blood tumors in the same period, which is similar to the incidence of AML in children.