Globinogenic anemia retinopathy

Globulin-producing anemia, also known as sickle cell anemia, was first described by Herrick in 1910, and he discovered that "sickness" cells appeared in the blood of a black hemolytic anemia black man. Because it first occurred in countries along the Mediterranean, it is also called Mediterranean anemia. It was later found to occur in all parts of the world except the Mediterranean, also known as thalassemia. This is a genetic defect of hemoglobin, which has a complex genetic basis and can have a variety of different gene mutations. It is a group of relatively impure hemoglobin synthesis disorders. It can be divided into homozygotes and heterozygotes, and can also be combined with other hemoglobin with abnormal properties to form a double heterozygote state. The disease can be divided into several categories, such as sickle cell anaemia, referred to as Sthal disease; sickle cell anemia, or SS disease; sickle cell C disease (SC disease); sickle cell characteristics ( sickle cell trait), also known as AS hemoglobin disease. The severity of ocular lesions varies according to the type, with complications most severe in Sthal and SC eyes.