Amyloidosis and amyloid arthropathy

Amyloidosis is a group of clinical symptoms caused by multiple causes, not a clinically independent disease, but a group of protein deposition diseases driven by tissue structure. The disease was first discovered by Wirchow in 1854. In the past 20 years, as amyloid was extracted from the tissues of patients with various diseases, its corresponding chemical components were further analyzed and understood, and the diagnosis rate was also significantly improved. The disease is not uncommon clinically. It is characterized by the deposition of amyloid substances in the blood vessel walls and tissues causing a variety of lesions, mainly involving the heart, kidney, liver, spleen, gastrointestinal, joint muscles and skin and other organs and tissues. Deposition can occur locally or systemically, and the course can be benign or malignant. The deposition of amyloid is often a partial manifestation of underlying conditions, and the related disease states may be inflammation, autoimmune diseases, genetic diseases and tumors, whose symptoms depend on the original disease and the location and amount of amyloid deposition.