Serum troponin

Troponin is a complex composed of 3 subunits, namely troponin C, troponin I, and troponin T. Troponin (cTn) is considered to be the most specific biochemical marker currently used in the diagnosis of ACS. They appear early and can appear as early as 2 hours after the onset of symptoms; they have a wide diagnostic window: cTnT (5-14 days), cTnI 4-10 days). In their diagnostic window, the increase of cTn is 5-10 times higher than that of CK-MB. Because the content of cTn in the blood is very low when there is no myocardial injury, it can also be used for the diagnosis of minor mycardial damage (MMD, micro myocardial damage), which is difficult to achieve by previous enzymatic indicators. cTn also has prognostic value. For any patient with coronary artery disease, even if the ECG or other tests (such as exercise tests) are negative, as long as cTn increases, it should be regarded as high risk.