Well differentiated squamous cell carcinoma

Squamous cell carcinoma is an abbreviation for squamous cell carcinoma, which often occurs in the areas covered by the original squamous epithelium of the body, such as the skin, lips, oral cavity, esophagus, throat, cervix, vagina, penis, etc. Some parts, such as the bronchus, gallbladder, and renal pelvis, are not normally covered by squamous epithelium, but squamous cell carcinoma can occur through pathological evolution of squamous metaplasia. This cancer is often cauliflower-like on the naked eye, and can also form ulcers due to necrosis of cancerous tissue. At the same time, the cancerous tissue is invasively growing deeper. Under the microscope, in the cancerous nests of differentiated squamous cell carcinomas, intercellular bridges can also be seen between the cells, and layered keratins can appear in the center of the cancerous nests, called keratin pearls or cancer Beads (see illustration). Poorly differentiated squamous cell carcinomas have no keratinized beads and even no intercellular bridges. The tumor cells are obviously atyptic and have more mitotic images.