Erythrocyte surface charge

The surface of red blood cells are all negatively charged. When the negatively charged red blood cells are placed in an electric field, they will move toward the positive electrode. Under the conditions of the same electric field strength and suspended ion strength, the faster the cell moves, the higher the cell surface charge density. , On the contrary, the lower. The amount of red blood cell surface charge is mainly the amount of sialic acid on the red blood cell membrane, the more the substance, the more negative charge. At present, the detection method of the surface charge of red blood cells is mainly detected by an invisible capillary cell electrophoresis apparatus. Its value can be expressed in two ways: one is cell electrophoresis time; the other is cell electrophoresis rate.