Autosomal dominant genetic disease

Autosomal dominant genetic disease, disease name. One of the single gene disease types. Refers to the disease caused by the dominant gene on the autosomal chromosomes. The so-called narrowness, that is, whether the pathogenic gene is homozygous (both alleles are causative) or heterozygous (one of the alleles is a pathogenic gene and the other is a normal gene) can cause disease . When the body obtains an autosome with a pathogenic gene from the germ cells of the previous generation, it can develop disease. The majority of patients with an autosomal dominant genetic disease are heterozygous for a dominant gene (heterozygote). If homozygous (homozygous), the condition is severe and often fatal (abortion, stillbirth, or neonatal death).